InVitroCYPTM H-Class Individual Human Liver Microsomes

Liver microsomes provide a readily available and well-characterized biological model for use in CYP enzyme inhibition studies. InVitroCYP H-class individual human liver microsomes are prepared from tissues that are screened and selected for high activity across the panel of relevant cytochrome P450 enzymes, including those CYPs that are traditionally low in activity. This microsome classification provides researchers with enhanced sensitivity on typically low activity CYPs.

 

Features and Benefits

  • Quality. Celsis IVT microsomes are quality checked by our independent quality control and quality assurance lab to guarantee quality and consistency.
  • Characterization. Celsis' extensive characterization and tissue profiling process guarantees that each lot of InVitroCYP microsomes will provide consistent and reproducible results.

  • Readily Available. Each product is produced in large batches, so you can consistently use the same lot of microsomes across experiments.

  • Choice. Available in 10- and 20-mg sizes.

 

The protein concentrations listed in the following tables are approximate. Please check the product data sheet for lot-specific protein content. InVitroCYP human liver microsomes are sold in vials of 0.5 mL (10 mg) and 1 mL (20 mg). Characterization information is available here.

 

Product No.DescriptionQuantity
F008084 InVitroCYP H-Class Human Liver Microsomes, Individual Female 10 mg
F008085 InVitroCYP H-Class Human Liver Microsomes, Individual Female 20 mg
M008084 InVitroCYP H-Class Human Liver Microsomes, Individual Male 10 mg
M008085 InVitroCYP H-Class Human Liver Microsomes, Individual Male 20 mg

 

Storage
InVitroCYP human liver microsomes must be stored in a mechanical cryogenic freezer below -70°C to guarantee the preservation of cytochrome P450 enzymes.

Stability
Historical data demonstrates that when stored under the recommended conditions, our human liver microsomes are stable for five (5) years. Celsis IVT is continually performing stability studies, following ICH guidelines, to validate and extend product shelf life.