H-Class Microsomes

Liver microsomes provide a readily available and well-characterized biological model for use in CYP enzyme inhibition studies. InVitroCYP H-class microsomes are prepared from tissues that are screened and selected for high activity across the panel of relevant cytochrome P450 enzymes, including those CYPs that are traditionally low in activity. This microsome classification provides researchers with enhanced sensitivity on typically low activity CYPs.

 

Features and Benefits

 
■  Pooled. Purpose-pooledSM using a proprietary alogorithm to achieve targeted high enzyme levels.

■  Quality. Celsis IVT microsomes are quality checked by our independent quality control and quality assurance lab to guarantee quality and 
    consistency.

■  Characterization. Celsis' extensive characterization and tissue profiling process guarantees that each lot of InVitroCYP microsomes will
    provide consistent and reproducible results.

■  Readily Available. Each product is produced in large batches, so you can consistently use the same lot of microsomes across experiments.

■  Choice. Available in 10-, 20-, and 100-mg sizes.

The protein concentrations listed in the following tables are approximate. Please check the product data sheet for lot-specific protein content. InVitroCYP human liver microsomes are sold in vials of 0.5 mL (10 mg), 1 mL (20 mg), and 5 mL (100 mg). Characterization information is available here.

 

Available Products 


 H-Class Microsomes Cells


Product No.Description

X008061

InVitroCYP H-class 10-Donor Pooled Human Liver Microsomes, 10 mg

FX008061

InVitroCYP H-class 10-Donor Female Pooled Human Liver Microsomes, 10 mg

X008063 InVitroCYP H-class 10-Donor Pooled Human Liver Microsomes, 100 mg
FX008061 InVitroCYP H-class 10-Donor Female Pooled Human Liver Microsomes, 10 mg
FX008062 InVitroCYP H-class 10-Donor Female Pooled Human Liver Microsomes, 20 mg
MX008061 InVitroCYP H-class 10-Donor Male Pooled Human Liver Microsomes, 10 mg
MX008062 InVitroCYP H-class 10-Donor Male Pooled Human Liver Microsomes, 20 mg
X008064 InVitroCYP H-class 25-Donor Pooled Human Liver Microsomes, 10 mg
X008065 InVitroCYP H-class 25-Donor Pooled Human Liver Microsomes, 20 mg
X008066 InVitroCYP H-class 25-Donor Pooled Human Liver Microsomes, 100 mg
FX008064 InVitroCYP H-class 25-Donor Female Pooled Human Liver Microsomes, 10 mg
FX008065 InVitroCYP H-class 25-Donor Female Pooled Human Liver Microsomes, 20 mg
MX008064 InVitroCYP H-class 25-Donor Male Pooled Human Liver Microsomes, 10 mg
MX008065 InVitroCYP H-class 25-Donor Male Pooled Human Liver Microsomes, 20 mg
F008084 InVitroCYP H-class Individual Female Human Liver Microsomes, 10 mg
F008085 InVitroCYP H-class Individual Female Human Liver Microsomes, 20 mg
M008084 InVitroCYP H-class Individual Male Human Liver Microsomes, 10 mg
M008085 InVitroCYP H-class Individual Male Human Liver Microsomes, 20 mg

 

Storage
InVitroCYP human liver microsomes must be stored in a mechanical cryogenic freezer below -70°C to guarantee the preservation of cytochrome P450 enzymes.

Stability
Historical data demonstrates that when stored under the recommended conditions, our human liver microsomes are stable for five (5) years. Celsis IVT is continually performing stability studies, following ICH guidelines, to validate and extend product shelf life.

For questions about Celsis In Vitro Technologies InVitroCYP Microsomes, contact Celsis IVT or call Customer Service at (888) 488-3232