M-Class Microsomes

Human liver microsomes are subcellular fractions that contain drug-metabolizing enzymes including CYP enzymes, flavin monooxygenases, and UDP glucuronyl transferases. InVitroCYP M-class microsomes are designed to exhibit moderate CYP activity, ideal for clearance and metabolite identification studies. Celsis' extensive characterization and tissue profiling process guarantees that each lot of InVitroCYP M-class microsomes will provide consistent and reproducible results for your metabolism and clearance studies.

Features and Benefits

■  Pooled. Purpose-pooledSM using a proprietary alogorithm to achieve targeted average enzyme levels.

■  Quality. Celsis IVT microsomes are quality checked by our independent quality control and quality assurance lab to guarantee quality and consistency

■  Characterization. Celsis' extensive characterization and tissue profiling process guarantees that each lot of InVitroCYP microsomes will provide consistent and reproducible results.

■  Readily Available. Each product is produced in large batches, so you can consistently use the same lot of microsomes across experiments.

■  Choice. Available in 10-, 20-, and 100-mg sizes.

The protein concentrations listed in the following tables are approximate. Please check the product data sheet for lot-specific protein content. InVitroCYP human liver microsomes are sold in vials of 0.5 mL (10 mg), 1 mL (20 mg), and 5 mL (100 mg). Characterization information is available here. 

Available Products 

 M-Class Microsomes Cells

Storage
InVitroCYP human liver microsomes must be stored in a mechanical cryogenic freezer below -70°C to guarantee the preservation of cytochrome P450 enzymes.

Stability
Historical data demonstrates that when stored under the recommended conditions, our human liver microsomes are stable for five (5) years. Celsis IVT is continually performing stability studies, following ICH guidelines, to validate and extend product shelf life.

For questions about InVitroCYP Microsomes, contact Celsis IVT or call Customer Service at (888) 488-3232